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Symbol
Name
ID

Ltb
lymphotoxin B
MGI:104796

Phenotype annotations related to hematopoietic system

Darker colors indicate more annotations

Mouse Phenotypes

spleen hyperplasia

abnormal class switch recombination

absent germinal center B cells

decreased marginal zone B cell number

increased lymphocyte cell number

increased leukocyte cell number

abnormal spleen morphology

abnormal spleen red pulp morphology

intermingled spleen red and white pulp

abnormal spleen white pulp morphology

abnormal spleen B cell follicle morphology

decreased spleen B cell follicle number

abnormal spleen follicular dendritic cell network

abnormal spleen germinal center morphology

absent spleen germinal center

decreased spleen germinal center number

decreased spleen germinal center size

abnormal spleen marginal zone morphology

absent spleen marginal zone

decreased spleen white pulp amount

decreased IgA level

decreased IgG1 level

decreased IgG2a level

decreased IgG level

increased IgM level

Availability

Mouse Genotype

Ltb/Tnf/Lta^tm1Dvk/Ltb/Tnf/Lta^tm1Dvk

Ltb/Tnf^tm1.1Dvk/Ltb/Tnf^tm1.1Dvk

Ltb^tm1Flv/Ltb^tm1Flv

Ltb^tm1Kpf/Ltb^tm1Kpf

Ltb^tm1Krn/Ltb^tm1Krn

Cd19^tm1(cre)Cgn/Cd19⁺
Ltb^tm1Avt/Ltb^tm1Avt (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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